"Bottleneck effect" in two-dimensional microfluidics.
نویسندگان
چکیده
An anomalously long transient is needed to achieve a steady pressurization of a fluid when forced to flow through micronarrowed channels under constant mechanical driving. This phenomenon, known as the "bottleneck effect" is here revisited from a different perspective, by using confined displacements of interfacial fluids. Compared to standard microfluidics, such effect admits in this case a neat quantitative characterization, which reveals intrinsic material characteristics of flowing monolayers and permits to envisage strategies for their controlled micromanipulation.
منابع مشابه
A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis
Antimicrobial resistance presents one of the most significant threats to human health, with the emergence of totally drug-resistant organisms. We have combined bioengineering, genetically modified bacteria, longitudinal readouts, and fluidics to develop a transformative platform to address the drug development bottleneck, utilizing Mycobacterium tuberculosis as the model organism. We generated ...
متن کاملLight actuation of liquid by optoelectrowetting
Optical actuation of liquid droplets has been experimentally demonstrated for the first time using a novel optoelectrowetting (OEW) principle. The optoelectrowetting surface is realized by integrating a photoconductive material underneath a two-dimensional array of electrowetting electrodes. Contact angle change as large as 308 has been achieved when illuminated by a light beam with an intensit...
متن کاملDynamics analysis of microparticles in inertial microfluidics for biomedical applications
Inertial microfluidics-based devices have recently attracted much interest and attention due to their simple structure, high throughput, fast processing and low cost. They have been utilised in a wide range of applications in microtechnology, especially for sorting and separating microparticles. This novel class of microfluidics-based devices works based on intrinsic forces, which cause micropa...
متن کاملA Bioengineered 3 - Dimensional Cell Culture Platform Integrated With 2 Microfluidics to Address Antimicrobial Resistance in Tuberculosis 3 4 Running title : Bioengineering to combat antimicrobial resistance 5 6 7
29 30 Antimicrobial resistance presents one of the most significant threats to human health, with the 31 emergence of totally drug-resistant organisms. We combine bioengineering, genetically 32 modified bacteria, longitudinal readouts and fluidics to develop a transformative platform to 33 address the drug development bottleneck, utilising Mycobacterium tuberculosis as the model 34 organism. We...
متن کاملAn algorithm for integrated worker assignment, mixed-model two-sided assembly line balancing and bottleneck analysis
This paper addresses a multi-objective mixed-model two-sided assembly line balancing and worker assignment with bottleneck analysis when the task times are dependent on the worker’s skill. This problem is known as NP-hard class, thus, a hybrid cyclic-hierarchical algorithm is presented for solving it. The algorithm is based on Particle Swarm Optimization (PSO) and Theory of Constraints (TOC) an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Physical review letters
دوره 100 13 شماره
صفحات -
تاریخ انتشار 2008